Displaying items by tag: design

Planning a cleanroom can be an overwhelming task! From site selection to calculating airflow changes and MEP requirements to clash coordination and onsite execution, there are no minor details. To hit your key dates for turnover and validation, your team needs to have an organized plan from the beginning. Below you will find helpful considerations, tips, and guides for designing and building your next cleanroom project.

Cleanrooms and controlled contamination environments are increasingly being used across many industrial sectors, including the pharmaceutical industry. An important issue is the operating cost associated with cleanroom energy consumption and, consequently, the identification of applicable energy containment measures. This article reviews pharmaceutical cleanroom calculations for non-unidirectional airflow against energy consumption with known sources of contamination and type of air diffusion used. It proposes alternative cases to compare potential economic savings from applying energy-saving measures proposed by ISO 14644-16.1

A Comprehensive Guide to These Essential Environments for High-Precision Manufacturing and Research, Highlighting the Applications, Maintenance and Cleaning Practices

When setting up a cleanroom, the placement of equipment and furniture should be properly configured for optimal airflow. Furniture that’s placed incorrectly can negatively impact circulation, thus creating blockages in airflow and stagnation and ultimately increasing the likelihood for contamination to occur.

The effects of the global COVID-19 pandemic have led to companies adapting their facilities to include a cleanroom area for product diversification, or expanding an existing cleanroom due to an increase in product demand such as ventilators and medical devices. So for many looking to upgrade or expand facilities, what are the best practice considerations for cleanroom design?

When designing a cleanroom, there are many aspects to take into consideration. While regulations and guidelines such as USP chapters outline the minimum requirements for cleanroom design, they do not address all important elements. Many compounding pharmacies use the requirements stated in USP chapters <797> and <800> as the template for designing their cleanroom—often at the expense of a workflow that is operationally efficient and designed to minimize contamination risk. To help compounding pharmacies stay compliant and reduce risk without sacrificing efficiency, here are some of the aspects to consider when designing a clean room, as well as some recommendations that we at Eagle consider best practices.

Cleanrooms are critical spaces in many industries where it is essential to maintain a controlled environment to prevent contamination of products or experiments. From pharmaceuticals to microelectronics, cleanrooms play a crucial role in ensuring product quality and safety.  

Reliable cleanrooms are specially constructed, enclosed spaces designed to regulate airborne particles, temperature, humidity, air pressure and more. As a leader in designing and assembling ISO class-compliant cleanrooms, Clean Air Products takes industry-regulated requirements into consideration when creating high-performing, aesthetically appealing cleanrooms. We design and manufacture Federal Standard 209E-compliant recirculating and non-recirculating modular hard wall and soft wall cleanrooms in a range of standard and custom sizes and configurations based on your specific industry requirements.

Cleanroom walls, floors, doors, and other components get a lot of attention, but one of the most crucial elements of cleanroom construction is the ceiling. Cleanroom ceilings support many of the essential functions of the space, from housing fan filter units to supporting lighting and other electrical components, fire suppression systems, and more.

From the time of Swiss watchmakers, who used bell jars to prevent dust from falling on their timepieces, to the development of high-efficiency particulate air (HEPA) filters for atomic energy production, manufacturers have worked to limit airborne contamination in their production environments. Today, ISO standards still emphasize air filtration and air distribution requirements, but the science of cleanroom design has necessarily gone beyond air filtration to include all components of the room, including floors, walls and especially doors.