Displaying items by tag: contamination
A cleanroom or clean room is an environment, typically used in manufacturing or scientific research, with a low level of environmental pollutants such as dust, airborne microbes, aerosol particles, and chemical vapors. More accurately, a cleanroom has a controlled level of contamination that is specified by the number of particles per cubic meter at a specified particle size.
A cleanroom provides a controlled, isolated environment for handling contamination-sensitive substances or for protecting the exterior environment from dangerous substances in the controlled area. The density of sub-micron and larger airborne particle contamination inside a cleanroom is kept within tightly controlled limits by forcing clean, filtered air into the cleanroom.
We will look at several areas of concern to get a better idea of the overall picture of contamination control. These are the things that need to be considered when providing an effective contamination control program.
Let us compare the numbers of airborne particle or micro organism in cleanroom with our surrounding environment. The numbers of particles in general environment vary from time to time so that any fixed number cannot be determined, but roughly classified as shown in the diagram to the right. From this figure, you will see that such a clean condition in the highest class cleanroom cannot be found in the natural world, even in the upper area of stratosphere. Also, in the center of Pacific Ocean, the cleanliness level of the air is lower than that of middle class of cleanroom. In other words, cleanroom is an ultra clean space where airborne particles or micro organism are been eliminated, as we can never experience in our normal environment.
Personnel in critical areas may be monitored for microbial contamination utilizing contact plates. The contact plates monitor areas of the body that may interact with the sterile field or product exposure areas. These may include gloved hands, forearms, or other areas. Personnel monitoring is a good indication of how well personnel are gowning when they enter the clean room. Many companies utilize this testing for proficiency based training programs for clean room personnel.
Who is best suited to perform housekeeping in a clean environment? Those that work in the cleanroom, a special in-house cleaning team, or an outside cleaning service? There are advantages and disadvantages to each, say cleaning supply representatives.
Contamination control is easier than detection because you cannot test for every impurity. Even if a product does not come in direct contact with the cleanroom environment, it is still influenced by it. Convection and circulating air can carry particulates and microbes, while handling can transfer residue. Thorough cleaning and disinfection of the environment minimizes the potential for contaminants to adversely affect product quality.
Preventing the growth of microorganisms is essential in most cleanrooms that deal with food, biologicals, or pharmaceuticals. The best way to combat contamination is by constructing floors without cracks and holes so microorganisms cannot hide and propagate.
Contamination control is the generic term for all activities aiming to control the existence, growth and proliferation of contamination in certain areas. Contamination control may refer to the atmosphere as well as to surfaces, to particulate matter as well as to microbes and to contamination prevention as well as to decontamination.
Contamination poses a significant risk to technical processes, experiments or production activities, as well as to the individuals involved. Unguarded proliferation of contamination can quickly lead to product damage, yield reduction, product recalls and other outcomes highly detrimental to business. Products in a range of industries are recalled due to ineffective contamination control systems.